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Borja Robert 11 months ago
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pages/STOP2030___Web.md
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# [[2024/02/19]] Propuestas de cambios # [[2024/02/19]] Propuestas de cambios
- Hay que dejar claro que es un proyecto y ser mucho más concreto sobre los detalles del proyecto. No solo vaguedades. - Hay que dejar claro que es un proyecto y ser mucho más concreto sobre los detalles del proyecto. No solo vaguedades.
- Hay que incluir - Hay que incluir
- Objetivos generales y objetivos específicos del proyecto. - ## Objetivos generales y objetivos específicos del proyecto.
- *Overall goal*: Support the achievement of the [[WHO]] 2030 NTD Roadmap for [[STH]] and beyond - *Overall goal*: Support the achievement of the [[WHO]] 2030 NTD Roadmap for [[STH]] and beyond
- *Project purpose*: Advance and accelerate an innovative pharmacological tool to support the elimination goals against [[STH]] species, specially those poorly responsive to current treatment regimens - *Project purpose*: Advance and accelerate an innovative pharmacological tool to support the elimination goals against [[STH]] species, specially those poorly responsive to current treatment regimens
- *The intervention*: A single tablet, [[Fixed-Dose Combination]] of Ivermectin and [[Albendazole]] - *The intervention*: A single tablet, [[Fixed-Dose Combination]] of Ivermectin and [[Albendazole]]
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- Develop a model for sustainable supply and costing - Develop a model for sustainable supply and costing
- Model the impact of different use cases and scenarios - Model the impact of different use cases and scenarios
- Pilot antihelmintic resistance surveillance based on genetic epidemiology - Pilot antihelmintic resistance surveillance based on genetic epidemiology
- Objetivos y logros de los proyectos STOP previos en background - ## Objetivos y logros de los proyectos STOP previos en background
- Qualification at EMA for art. 58 - Qualification at EMA for art. 58
- Safety of IVM up to 600μg/kg alone and in coformulation with albendazole - Safety of IVM up to 600μg/kg alone and in coformulation with albendazole
- Demonstrated efficacy agrainst T. trichiura in a pivotal trial in Sub-Saharan Africa - Demonstrated efficacy agrainst T. trichiura in a pivotal trial in Sub-Saharan Africa

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